ea0016p371 | Growth factors | ECE2008
Meyer Silke
, Bruck Carolin
, Ivan Diana
, Kohler Ute
, Schafer Stephan
, Arp Pascal
, van der Lely Aart J
, Uitterlinden Andre G
, Kann Peter H
Objective: A cytosine-adenine (CA)n microsatellite repeat polymorphism in the promoter region of the insulin-like growth factor-1 (IGF-1) gene has reported to be associated with IGF-1 serum levels, birth weight, body height, bone mineral density and risk for type 2 diabetes and myocardial infarction. Carriers and non-carriers of the most frequent allele (length 192 base pairs (bp)) showed significantly different total IGF-1 serum levels. This polymorphism may direct...